The smart Trick of ceesdekker That Nobody is Discussing
The smart Trick of ceesdekker That Nobody is Discussing
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Nanotechnology delivers A selection of alternatives to lead to biology. Below I'll existing illustrations where by nanofabrication – a chance to make confined structures with dimensions at will – is used to examine the biophysics of single molecules and cells. I will existing some illustrations from our lab:
1996, initial mesoscopic demand density waves gadgets; and 1st electrical measurements on a single steel nanocluster concerning nanoelectrodes
‘It had been merely a matter of finding up a ebook on cell biology and beginning to examine. I had originate from a earth of ultra-high vacuums, cryostats and quantum phenomena, and now I used to be Doing the job at area temperature with molecular biology kits.
Non-equilibrium folding of person DNA molecules recaptured as much as 1000 occasions inside a strong state nanopore
2010, developed a fresh way (‘wedging transfer’) to control nanostructures; initially report of DNA translocation through graphene nanopores; and realized hybrid nanopores by directed insertion of α-hemolysin into sound-condition nanopores
In the years next these discoveries, my exploration passions shifted to biophysics and nanobiology, and I became less linked to the event of nanotube electronics. The focus of numerous researchers in the field also shifted to graphene (where, funnily more than enough, the 1st graphene ribbons ended up referred to as ‘nanotubes which are cut open up alongside their length’) after the invention of the two-dimensional material in 2004.
We shape bacteria into forms that deviate from their natural phenotype. Specifically, I'll exhibit our capacity to form Reside E. coli bacteria into novel styles for example rectangles, squares, triangles and circles.
2000, discovery that nanotubes can have extraordinary massive present-day densities; settled the controversial challenge of Digital transport by way of DNA molecules by measurements of insulating actions at the single molecule degree; and demonstration of the AFM technique for single-molecule manipulation of nanotubes
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Presently, we also understood that it ought to be attainable to work with an individual semiconducting carbon nanotube to generate a transistor — and we set out to make it. We stretched person semiconducting nanotubes across metallic electrodes and made use of the fundamental silicon substrate being a gate electrode, setting up the basic three-terminal structure of the discipline-impact transistor (Fig.
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Cees Dekker is Distinguished College Professor at TU Delft. Properly trained as a physicist, he pioneered nanotechnology with many discoveries on carbon nanotubes within the 1990s. Given that 2000, he moved to solitary-molecule biophysics and nanobiology. His existing analysis focuses on (i) nanopores for protein sequencing; (ii) chromosome structure, in particular SMC motor protein; and (iii) developing a dwelling artificial mobile from lifeless molecules. Dekker is undoubtedly an elected member on the KNAW and fellow for the APS as well as the IOP.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij fulfilled enkel-molecuultechnieken de biofysica van moleculen in de biologische https://www.ceesdekker.net cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent design and style in 2005. (nl)